PPARGC1B Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
Abbreviation
PPARGC1B
UniProt
Q86YN6
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human PPARGC1B
Target
PERC; peroxisome proliferative activated receptor; gamma; coactivator 1; ; peroxisome proliferator-activated receptor gamma coactivator 1 beta; Peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma; coactivator 1 beta; PGC-1 (beta) ; PGC-1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC1; PPAR gamma coactivator-1beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PPARGC1; Ppargc1b; PRGC2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Signal transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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