OMG Polyclonal Antibody
Product Specifications
Background
Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS) . OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells; from dorsal root ganglion explants in which growth cone collapse was observed; from rat retinal ganglion neurons; and from NG108 and PC-12 cells.
Abbreviation
OMG
UniProt
P23515
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human OMG
Target
Oligodendrocyte-myelin glycoprotein; Omg; OMGP; OMGP
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Neuroscience
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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