NLRP10 Polyclonal Antibody

Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD) . The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

CLR11.1; NACHT; leucine rich repeat and PYD containing 10; NACHT; LRR and PYD domains containing protein 10; NACHT; LRR and PYD domains-containing protein 10; NAL10; NALP10; NLR family; pyrin domain containing 10; Nlrp10; NOD8; Nucleotide-binding oligomerization domain protein 8; Nucleotide-binding oligomerization domain; leucine rich repeat and pyrin domain containing 10; PAN5; PYNOD