NLRP6 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
NLRP6
UniProt
P59044
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human NLRP6
Target
Angiotensin II/vasopressin receptor; AVR; CLR11.4; NACHT; leucine rich repeat and PYD containing 6; NACHT; LRR and PYD containing protein 6; NACHT; LRR and PYD domains-containing protein 6; NAVR; NAVR/AVR; NLR family; pyrin domain containing 6; Nlrp6; NLRP6; Nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 6; PAN3; PYPAF5; PYRIN containing APAF1 like protein 5; PYRIN-containing APAF1-like protein 5
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell biology; Immunology; Signal transduction
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/wpzqlk
Product MSDS
https://789.bio/eb/SurTu1
Isotype
IgG
Available Sizes
Curated Selection
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