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MRGPRX1 Polyclonal Antibody

Product Specifications

Background

MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) . BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.

Abbreviation

MRGPRX1

UniProt

Q96LB2

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human MRGPRX1

Target

GPCR; MAS related gene MRGX1; MAS related GPR member X1; MRGPRX1; MRGX1; SNSR4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Signal transduction

Purification

Affinity purification

Concentration

0.5 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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