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UBP1 Polyclonal Antibody

Product Specifications

Background

LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family) . LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.

Abbreviation

UBP1

UniProt

Q9NZI7

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human UBP1

Target

LBP1A; LBP1B; LBP-1B; LBP-1a

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.7 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

60kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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