IPO8 Polyclonal Antibody
Product Specifications
Background
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
IPO8
UniProt
O15397
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human IPO8
Target
FLJ26580; Imp 8; Imp8; Importin-8; Importin8; IPO 8; IPO8; IPO8; Ran binding protein 8; RAN BP8; Ran-binding protein 8; RANBP 8; RanBP8
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling; Signal transduction
Purification
Affinity purification
Concentration
1.2 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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