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DSC1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

Abbreviation

DSC1

UniProt

Q08554

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human DSC1

Target

Cadherin family member 1; CDHF1; Desmocollin1; Desmosomal glycoprotein 2/3; DG2/DG3; DSC 1; DSC1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Signal transduction

Purification

Affinity purification

Concentration

0.9 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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