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DEFA4 Polyclonal Antibody

Product Specifications

Background

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.

Abbreviation

DEFA4

UniProt

P12838

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human DEFA4

Target

HP4; DEF4; HP-4; HNP-4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Immunology; Microbiology

Purification

Affinity purification

Concentration

0.9 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/pwh8t1

Product MSDS

https://789.bio/eb/1KyLq1

Isotype

IgG

Available Sizes

Curated Selection

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