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BGLAP Polyclonal Antibody

Product Specifications

Background

Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner.

Abbreviation

BGLAP

UniProt

P02818

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human BGLAP

Target

BGLAP; BGP; Bone gamma carboxyglutamate (gla) protein; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gla protein; Gamma carboxyglutamic acid containing protein; Gamma-carboxyglutamic acid-containing protein; OC; OCN; OSTCN; Osteocalcin; OTTHUMP00000016586; PMF1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Signal transduction; Stem cells

Purification

Affinity purification

Concentration

0.6 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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