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BCAS4 Polyclonal Antibody

Product Specifications

Background

The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer.The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies.

Abbreviation

BCAS4

UniProt

Q8TDM0

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human BCAS4

Target

BCAS4; BCAS4/BCAS3 fusion; BCAS4; Breast carcinoma amplified sequence 4; Breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 4; CNOL; FLJ20495; RP5-1071L10.2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer

Purification

Affinity purification

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

23kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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