BCAS4 Polyclonal Antibody
Product Specifications
Background
The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer.The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies.
Abbreviation
BCAS4
UniProt
Q8TDM0
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human BCAS4
Target
BCAS4; BCAS4/BCAS3 fusion; BCAS4; Breast carcinoma amplified sequence 4; Breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 4; CNOL; FLJ20495; RP5-1071L10.2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23kDa
Isotype
IgG
Available Sizes
Curated Selection
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