LIN28B Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Abbreviation
LIN28B
UniProt
Q6ZN17
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human LIN28B
Target
CSDD 2; CSDD2; FLJ16517; Lin 28 homolog B (C. elegans) ; Lin 28.2; Lin-28B; LIN28B; LN28B; Protein lin-28 homolog B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
27kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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