ZFP42 Polyclonal Antibody
Product Specifications
Background
Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.
Abbreviation
ZFP42
UniProt
Q96MM3
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human ZFP42
Target
HREX-1; Reduced Expression 1 Protein; Reduced expression protein 1; Rex-1; REX1; REX1 transcription factor; Zfp-42; Zfp42; ZFP42 zinc finger protein; ZFP42; Zinc finger protein 42 homolog; Zinc finger protein 754; ZNF754
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Developmental Biology; Stem Cells
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
WB 1:200-1:1000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/pepgv1
Product MSDS
https://789.bio/eb/z9OKWD
Calculated Molecular Weight
35kDa
Isotype
IgG
Available Sizes
Curated Selection
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