ARHGEF11 Polyclonal Antibody
Product Specifications
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Abbreviation
ARHGEF11
UniProt
O15085
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human ARHGEF11
Target
ARHGB; ARHGEF 11; ARHGEF11; DKFZp667F1223; Glutamate transporter EAAT4 associated protein 48; GTRAP 48; GTRAP48; KIAA0380; OTTHUMP00000038716; OTTHUMP00000038717; PDZ RHOGEF; PDZ-RhoGEF; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; Rho guanine nucleotide exchange factor 11; RhoA specific guanine nucleotide exchange factor; RhoGEF glutamate transport modulator
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/hplkxs
Product MSDS
https://789.bio/eb/ajPmXT
Calculated Molecular Weight
168kDa
Isotype
IgG
Available Sizes
Curated Selection
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