ARAP1 Polyclonal Antibody

The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) -dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

2410002L19Rik; ANK repeat and PH domain-containing protein 1; ARAP 1; Arap1; ARAP1; Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1; Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1; Arf-GAP with Rho-GAP domain; CENT D2; Centaurin delta 2; Centaurin delta2; Centaurin-delta-2; CENTD 2; CENTD2; Cnt d2; Cnt-d2; Cntd2; KIAA0782; MGC176140; mKIAA0782