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GLRA1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Abbreviation

GLRA1

UniProt

P23415

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human GLRA1

Target

GLRA1; GLRA1; Glycine receptor 48 kDa subunit; Glycine receptor alpha 1; Glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; Glycine receptor; alpha 1 subunit; HKPX1; STHE

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience

Purification

Affinity purification

Concentration

0.2 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

53kDa

Isotype

IgG

Available Sizes

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