TNXB Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
TNXB
UniProt
P22105
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human TNXB
Target
EDS3; Ehlers Danlos like syndrome; Growth inhibiting protein 45; Hexabrachion like protein; Hexabrachion-like protein; HXBL; NXB2; Tenascin X precursor; Tenascin XB; Tenascin XB1; Tenascin XB2; Tenascin-X; TENX; TENX; TN X; TN-X; TNX; TNXB; TNXB1; TNXB2; TNXBS; VUR8; XB; XBS
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/vhgtqp
Product MSDS
https://789.bio/eb/vnTKyP
Isotype
IgG
Available Sizes
Curated Selection
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View Details OR1073809-04 25 mg
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View Details OR1073809-05 50 mg
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