SFRP1 Polyclonal Antibody

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

Frizzled related protein 1; FRP 1; FRP; FRP-1; FRP1; FrzA; SARP 2; SARP-2; SARP2; Secreted apoptosis related protein 2; Secreted apoptosis-related protein 2; Secreted frizzled related protein 1; Secreted frizzled related protein; Secreted frizzled-related protein 1; SFRP 1; sFRP-1; SFRP1; SFRP1