MUC5B Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.
Abbreviation
MUC5B
UniProt
Q9HC84
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human MUC5B
Target
2300002I04Rik; A130042M24; AV085033; Cervical mucin; Cervical mucin MUC5B; High molecular weight salivary mucin MG1; MG1; MUC-5B; MUC5; MUC5B; MUC5B; MUC9; Mucin 5 subtype B; tracheobronchial; Mucin 5B; Mucin 5B oligomeric mucus/gel forming; Mucin-5 subtype B; Mucin-5B; Sublingual gland mucin; tracheobronchial
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01
https://www.sciencedirect.com/science/article/pii/S2352396419307820
Citation 02
https://europepmc.org/article/pmc/pmc8842394?javascript_support=no
Citation 03
https://www.mdpi.com/1422-0067/22/13/6657
Citation 04
https://portlandpress.com/bioscirep/article-abstract/doi/10.1042/BSR20222669/232576
Isotype
IgG
Available Sizes
Curated Selection
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