SOCS7 Polyclonal Antibody
Product Specifications
Background
The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
Abbreviation
SOCS7
UniProt
O14512
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human SOCS7
Target
Ash and phospholipase C gamma-binding protein; NAP 4; NAP 4 Fragment; NAP-4; NAP4; Nck; Nck Ash and phospholipase C binding protein; Nck Ash and phospholipase C gamma binding protein; Nck associated protein 4; Nck-associated protein 4; NCKAP4; SH2 domain containing SOCS box protein; SOCS 7; SOCS-7; SOCS4; SOCS6; Socs7; SOCS7; Suppressor of cytokine signaling 7
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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