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HDAC1 Polyclonal Antibody

Product Specifications

Background

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Abbreviation

HDAC1

UniProt

Q13547

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human HDAC1

Target

DKFZp686H12203; GON 10; HD1; HDAC 1; HDAC1; HDAC1; Histone deacetylase 1; Reduced potassium dependency yeast homolog like 1; RPD3; RPD3L1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Stem Cells

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:200-1:1000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/d0dyho

Product MSDS

https://789.bio/eb/GuLyj9

Calculated Molecular Weight

55kDa

Isotype

IgG

Available Sizes

Curated Selection

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