HCN2 Polyclonal Antibody
Product Specifications
Background
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih) . Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.
Abbreviation
HCN2
UniProt
Q9UL51
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human HCN2
Target
BCNG-2; BCNG2; Brain cyclic nucleotide gated channel 2; Brain cyclic nucleotide-gated channel 2; HAC1; Hcn2; HCN2; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cardiovascular; Neuroscience
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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