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GFRA3 Polyclonal Antibody

Product Specifications

Background

GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

Abbreviation

GFRA3

UniProt

O60609

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human GFRA3

Target

GDNF family receptor alpha 3; GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNFR-alpha-3; GDNFR3; GFR-alpha-3; GFRA3; GFRA3; Glial cell line derived neurotrophic factor receptor alpha 3; GPI linked receptor; OTTHUMP00000159486; OTTHUMP00000224020

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Neuroscience

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

IHC 1:50-1:150

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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