GFRA3 Polyclonal Antibody
Product Specifications
Background
GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.
Abbreviation
GFRA3
UniProt
O60609
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human GFRA3
Target
GDNF family receptor alpha 3; GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNFR-alpha-3; GDNFR3; GFR-alpha-3; GFRA3; GFRA3; Glial cell line derived neurotrophic factor receptor alpha 3; GPI linked receptor; OTTHUMP00000159486; OTTHUMP00000224020
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Neuroscience
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
IHC 1:50-1:150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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