STAR Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
Abbreviation
STAR
UniProt
P49675
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human STAR
Target
Cholesterol trafficker; Luteinizing hormone induced protein; mitochondrial; Mitochondrial steroid acute regulatory protein; StAR; StAR related lipid transfer (START) domain containing 1; STAR; StARD1; START domain containing 1; START domain containing protein 1; START domain-containing protein 1; Steroid acute regulatory protein; Steroidogenic acute regulator; Steroidogenic acute regulatory protein; Steroidogenic acute regulatory protein mitochondrial
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32kDa
Citation 01
https://www.mdpi.com/1422-0067/22/15/8094
Citation 02
https://www.frontiersin.org/articles/10.3389/fendo.2020.00302/full
Citation 03
https://www.mdpi.com/954398
Citation 04
https://onlinelibrary.wiley.com/doi/abs/10.1002/jez.2609
Isotype
IgG
Available Sizes
Curated Selection
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