DHCR24 Polyclonal Antibody
Product Specifications
Background
This gene encodes a flavin adenine dinucleotide (FAD) -dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Abbreviation
DHCR24
UniProt
Q15392
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human DHCR24
Target
24 dehydrocholesterol reductase;24-dehydrocholesterol reductase;3 beta hydroxysterol delta 24 reductase;3-beta-hydroxysterol delta-24-reductase; DCE; Delta (24) -sterol reductase; Desmosterol to cholesterol enzyme; DHC24; Dhcr24; Diminuto dwarf1 homolog; Diminuto/dwarf1 homolog; KIAA0018; Nbla03646; Seladin-1; SELADIN1; Selective AD indicator 1; Selective Alzheimer's Disease Indicator 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Cardiovascular; Metabolism; Neuroscience
Purification
Affinity purification
Concentration
0.7 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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