MCTS1 Polyclonal Antibody
Product Specifications
Background
MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
Abbreviation
MCTS1
UniProt
Q9ULC4
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human MCTS1
Target
FLJ39637; Malignant T cell-amplified sequence 1; MCT 1; MCT-1; MCT1; MCTS 1; MCTS1; MCTS1; Multiple copies T cell malignancies 1; Multiple copies T cell malignancies; Multiple copies T-cell malignancies; Oncogene MCT 1; Oncogene MCT1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21kDa
Isotype
IgG
Available Sizes
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