LZTFL1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.
Abbreviation
LZTFL1
UniProt
Q9NQ48
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human LZTFL1
Target
5530402H04Rik;6130400H19Rik; AI414725; AW048545; BBS17; DKFZp686H2076; FLJ36386; Leucine zipper transcription factor like 1; Leucine zipper transcription factor like protein 1; Leucine zipper transcription factor-like protein 1; LZTFL 1; Lztfl1; Lztfl1 leucine zipper transcription factor-like 1; LZTL1; MGC106871; MGC108960; Putative uncharacterized protein DKFZp686H2076
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/4v1krc
Product MSDS
https://789.bio/eb/GyPOu1
Calculated Molecular Weight
35kDa
Isotype
IgG
Available Sizes
Curated Selection
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