LDOC1 Polyclonal Antibody

The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

BCUR1; Breast cancer up regulated 1; Breast cancer upregulated 1; Gm366; Ldoc1; LDOC1; Leucine zipper down regulated in cancer 1; Leucine zipper protein down regulated in cancer cells; Leucine zipper protein down regulated in cancer cells; Leucine zipper protein down-regulated in cancer cells; Mar7; Mart7; Protein LDOC1; RGD1565644