LBR Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Abbreviation
LBR
UniProt
Q14739
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human LBR
Target
DHCR 14B; DHCR14B; Integral nuclear envelope inner membrane protein; Lamin-B receptor; LBR; LBR; LMN 2R; LMN2R; MGC9041; PHA; PRO0650
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Signal Transduction; Tags and Cell Markers
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
71kDa
Isotype
IgG
Available Sizes
Curated Selection
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