HSD17B4 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD) . An apparent pseudogene of this gene is present on chromosome 8.
Abbreviation
HSD17B4
UniProt
P51659
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human HSD17B4
Target
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase;17 beta HSD 4;17 beta HSD IV;17 beta hydroxysteroid dehydrogenase 4;17-beta-HSD 4;17-beta-hydroxysteroid dehydrogenase 4;17beta estradiol dehydrogenase type IV;3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase;3-alpha;7-alpha; Beta hydroxyacyl dehydrogenase; Beta keto reductase; D 3 hydroxyacyl CoA dehydratase; D bifunctional protein; D bifunctional protein peroxisomal; D-3-hydroxyacyl CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein; D-bifunctional protein; D-bifunctional protein; peroxisomal; DBP; DBP; peroxisomal; DHB4; EDH17B4; Enoyl-CoA hydratase 2; Hsd17b4; MFE 2; MFE-2; MPF-2; Multifunctional protein 2; Peroxisomal multifunctional enzyme type 2; Peroxisomal multifunctional protein 2; PRLTS1; SDR8C1; Short chain dehydrogenase/reductase family 8C member 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
80kDa
Isotype
IgG
Available Sizes
Curated Selection
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