FGB Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Abbreviation
FGB
UniProt
P02675
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human FGB
Target
Epididymis secretory sperm binding protein Li 78p; FGB; FIBB; Fibrinogen B beta polypeptide; Fibrinogen beta chain; Fibrinogen beta polypeptide chain; Fibrinopeptide B; HEL S 78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC104327; MGC120405; OTTHUMP00000197066
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cardiovascular
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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