FGFR1OP2 Polyclonal Antibody
Product Specifications
Background
Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors which include the Flg receptor (FGFR-1) and the Bek receptor (FGFR-2), as well as FGFR-3, FGFR-4, FGFR-5 and FGFR-6. FGFR1OP2 (FGFR1 oncogene partner 2), also known as HSPC123, is a 253 amino acid cytoplasmic protein that is expressed in spleen, thymus and bone marrow and is involved in wound healing under normal cellular conditions. Additionally, FGFR1OP2 may also exist as an aberrant fusion protein with Flg and it is thought that the FGFR1OP2-Flg mutant may play a role in the pathogenesis of stem cell myeloproliferative disorder (MPD) . Multiple isoforms of FGFR1OP2 exist due to alternative splicing events.
Abbreviation
FGFR1OP2
UniProt
Q9NVK5
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human FGFR1OP2
Target
DKFZp564O1863; FGFR1 oncogene partner 2; FGFR1OP2; FGOP2; Fibroblast growth factor receptor 1 oncogene partner 2; HSPC123; HSPC123 like; WIT3.0; Wound inducible transcript 3.0
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/pm1zi1
Product MSDS
https://789.bio/eb/yvHKqT
Isotype
IgG
Available Sizes
Curated Selection
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