EIF3H Polyclonal Antibody
Product Specifications
Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Abbreviation
EIF3H
UniProt
O15372
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human EIF3H
Target
EIF-3-gamma; eIF3 gamma; eIF3 p40; eIF3 p40 subunit; eIF3h; EIF3H; EIF3S3; Eukaryotic translation initiation factor 3 subunit 3; Eukaryotic translation initiation factor 3 subunit H; MGC102958
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/kzsgtl
Product MSDS
https://789.bio/eb/GS8GOK
Calculated Molecular Weight
40kDa
Isotype
IgG
Available Sizes
Curated Selection
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