FBXW7 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.
Abbreviation
FBXW7
UniProt
Q969H0
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human FBXW7
Target
AGO; Archipelago; Archipelago homolog; Archipelago; Drosophila; homolog of; CDC4; CDC4; S.cerevisiae; homolog of; DKFZp686F23254; F box and WD 40 domain protein 7 (archipelago homolog; Drosophila) ; F box and WD 40 domain protein 7; F box and WD repeat domain containing 7; F box protein FBW7; F box protein FBX30; F box protein SEL 10; F box protein SEL10; F-box and WD repeat domain containing 7; E3 ubiquitin protein ligase; F-box and WD-40 domain-containing protein 7; F-box protein FBX30; F-box/WD repeat-containing protein 7; FBW6; FBW7; FBX30; FBXO30; FBXW6; FBXW7; FBXW7; FLJ16457; hAgo; hCdc4; Homolog of C elegans sel 10; Homolog of C.elegans sel10; SEL 10; SEL-10; SEL10
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/uw1o8r
Product MSDS
https://789.bio/eb/Sm504G
Isotype
IgG
Available Sizes
Curated Selection
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