KIR2DL1/3/4/S4 Polyclonal Antibody

Product Specifications

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain.

Abbreviation

KIR2DL3/1/4/S4

UniProt

P43628, P43626, Q99706

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human KIR2DL3/1/4/S4

Target

P58; NKAT; GL183; NKAT2; CD158b; NKAT2A; NKAT2B; CD158B2; KIR-K7b; KIR-K7c; KIRCL23; KIR-023GB/NKAT; NKAT1; p58.1; CD158A; KIR221; KIR-K64/ G9P; CD158D; KIR103; KIR103AS/ KKA3; KIR1D; NKAT8; CD158I; KIR412