BPI Polyclonal Antibody

This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Bactericidal permeability-increasing protein; Bactericidal/permeability increasing protein; BPI; BPI fold containing family D; member 1; BPI; BPIFD1; CAP 57; CAP57; rBPI; Recombinant BPI holoprotein; rBPI