ABI3BP Polyclonal Antibody

A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

ABI gene family member 3 (NESH) binding protein; ABI gene family member 3 binding protein; ABI gene family member 3-binding protein; ABI3BP; FLJ41743; FLJ41754; Nesh binding protein; Nesh BP; Nesh-binding protein; NeshBP; Target of Nesh SH3; Target of Nesh-SH3; Tarsh; TARSH