ASCC1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF) . The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Abbreviation
ASCC1
UniProt
Q8N9N2
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human ASCC1
Target
Activating signal cointegrator 1 complex subunit 1; ASC-1 complex subunit p50; ASC1 complex subunit p50; ASC1p50; ASCC1; ASCC1; CGI 18; RP11-150D20.4; Trip4 complex subunit p50
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/wpk8zs
Product MSDS
https://789.bio/eb/f50SeD
Isotype
IgG
Available Sizes
Curated Selection
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