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CERK Polyclonal Antibody

Product Specifications

Background

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

Abbreviation

CERK

UniProt

Q8TCT0

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human CERK

Target

Acylsphingosine kinase; Ceramide kinase; Cerk; CERK1; dA59H18.2; dA59H18.3; hCERK; KIAA1646; Lipid kinase 4; Lipid kinase LK4; LK4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cell Biology

Purification

Affinity purification

Concentration

0.4 mg/mL

Dilution

IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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