HK2 Polyclonal Antibody

Product Specifications

Background

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Abbreviation

HK2

UniProt

P52789

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human HK2

Target

DKFZp686M1669; Hexokinase 2; Hexokinase 2 muscle; Hexokinase type II; Hexokinase-2; HK 2; HK II; HK2; HKII; HxK 2; HxK2; HXK2; Muscle form hexokinase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cardiovascular; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

0.6 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:100-1:300

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

102kDa

Citation 01

https://link.springer.com/article/10.1186/s12929-022-00855-6

Citation 02

https://www.frontiersin.org/articles/10.3389/fonc.2021.618705/full

Citation 03

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279700/

Isotype

IgG

Available Sizes

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