STK40 Polyclonal Antibody
Product Specifications
Background
STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.
Abbreviation
STK40
UniProt
Q8N2I9
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human STK40
Target
2310004N11Rik; MGC4796; OTTHUMP00000009948; OTTHUMP00000009951; RP11-268J15.4; Ser/Thr like kinase; Serine/threonine kinase 40; Serine/threonine protein kinase 40; SgK495; SHIK; SINK homologous serine/threonine protein kinase; SINK-homologous inhibitory kinase; STK 40; Sugen kinase 495
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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