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PKC delta Polyclonal Antibody

Product Specifications

Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Abbreviation

PRKCD

UniProt

Q05655

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human PRKCD

Target

CVID9; D14Ertd420e; Kinase PKC delta; KPCD; KPCD; MAY 1; MAY1; MGC49908; nPKC delta; nPKC-delta; PCKd; PKC d; PKC delta; PKCD; PKCdelta; PRKC D; PRKC delta; Prkcd; Protein Kinase C delta; Protein kinase C delta type; Protein kinase C delta VIII; Protein Kinase Cdelta; Tyrosine protein kinase PRKCD

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Neuroscience; Signal Transduction

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:200-1:1000; IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

78kDa

Citation 01

https://www.frontiersin.org/articles/10.3389/fonc.2021.735183/full

Isotype

IgG

Available Sizes

Curated Selection

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