AKR1D1 Polyclonal Antibody
Product Specifications
Background
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta (4) -3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Abbreviation
AKR1D1
UniProt
P51857
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human AKR1D1
Target
3-oxo-5-beta-steroid 4-dehydrogenase;3o5bred; AK1D1; AKR1D1; aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) ; Aldo keto reductase family 1 member D1; Aldo-keto reductase family 1 member D1; CBAS2; Delta (4) 3 ketosteroid 5 beta reductase; Delta (4) 3 oxosteroid 5 beta reductase; Delta (4) -3-ketosteroid 5-beta-reductase; Delta (4) -3-oxosteroid 5-beta-reductase; SRD5B1; steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) ; steroid 5 beta reductase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37kDa
Isotype
IgG
Available Sizes
Curated Selection
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