SPARC Polyclonal Antibody
Product Specifications
Background
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion.
Abbreviation
SPARC
UniProt
P09486
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human SPARC
Target
AA517111; Basement membrane protein 40; Basement-membrane protein 40; BM 40; BM-40; BM40; Cysteine rich protein; hm:zeh0062; MGC128090; OI17; ON; Osteonectin; Secreted acidic cystein rich glycoprotein; Secreted protein acidic and cysteine rich; Secreted protein acidic and rich in cysteine; Secreted protein acidic cysteine rich (osteonectin) ; Secreted protein acidic cysteine rich; SPARC; SPRC; SPRC
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Cardiovascular; Developmental Biology; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35kDa
Citation 01
https://journals.sagepub.com/doi/abs/10.1177/21925682221138766
Isotype
IgG
Available Sizes
Curated Selection
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