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CD159a/c Polyclonal Antibody

Product Specifications

Background

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

Abbreviation

KLRC1

UniProt

P26715

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human KLRC1

Target

C lectin type II protein; CD159 antigen like family member A; CD159 antigen-like family member A; CD159a; CD159a antigen; Killer cell lectin like receptor subfamily C member 1; KLRC1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer cell protein group 2-A1; Natural killer cell receptor NKG2A; Natural killer group protein 2; NK cell receptor A; NKG2 1/B activating NK receptor; NKG2 A; NKG2 A/B activating NK receptor; NKG2 A/B type II integral membrane protein; NKG2 A/NKG2 B type II integral membrane protein; NKG2; NKG2 B; NKG2-1/B activating NK receptor; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2A; NKG2A; NKG2B; rNKG2A

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Immunology

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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