1-Oleoyl-2-acetyl-sn-glycerol

1-Oleoyl-2-acetyl-sn glycerol is a synthetic, cell permeable diacylglycerol analog. 1-Oleoyl-2-acetyl-sn glycerol activates calcium-dependent protein kinase C (PKC) and induces the superoxide-production.

Product Specifications

CAS Number

[86390-77-4]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H331, H336, H351, H361, H372, H412

Target

PKC

Type

Reference compound

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/1-oleoyl-2-acetyl-sn-glycerol.html

Concentration

25.09 mM * 1 mL in Acetonitrile

Purity

99.90

Solubility

10 mM in DMSO

Smiles

OC[C@H](OC(C)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

Molecular Formula

C23H42O5

Molecular Weight

398.58

Precautions

H302, H315, H319, H331, H336, H351, H361, H372, H412

References & Citations

[1]Fujita I, Irita K, Takeshige K, Minakami S. Diacylglycerol, 1-oleoyl-2-acetyl-glycerol, stimulates superoxide-generation from human neutrophils. Biochem Biophys Res Commun. 1984;120 (2) :318-324. |[2]Martin AC, Cooper DM. Capacitative and 1-oleyl-2-acetyl-sn-glycerol-activated Ca (2+) entry distinguished using adenylyl cyclase type 8. Mol Pharmacol. 2006;70 (2) :769-777.