CFHR1 Polyclonal Antibody

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

CFHL; CFHL1; CFHL1P; CFHR1; CFHR1P; Complement factor H related 1; Complement factor H related 1 pseudogene; Complement factor H related protein 1 precursor; Complement factor H-related protein 1; FHR 1; FHR-1; FHR1; FHR1; H factor (complement) like 1; H factor (complement) like 2; H factor like protein 1; H factor-like protein 1; H-factor-like 1; H36 1; H36 2; H36; HFL1; HFL2; MGC104329