GSR Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Abbreviation
GSR
UniProt
P00390
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human GSR
Target
GLR1; GLUR; Glutathione reductase; Glutathione reductase mitochondrial; Glutathione reductase; mitochondrial; GR; Gr1; GRase; GRD 1; GRD1; GSHR; GSR; MGC78522
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56kDa
Isotype
IgG
Available Sizes
Curated Selection
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